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Three years of science are required for graduation to include biology and two physical science courses. All students enrolled in a biology course are administered the New Jersey Biology End-of-Course (EOC) Assessment in the spring.

Northern Burlington recommends this sequence:

Grade 9 - Biology/Biology of Agriscience/Honors Biology
Grade 10 - Physical Science/Environmental Science/Chemistry/Honors Chemistry
Grade 11 - Physical Science/Environmental Science/Chemistry/Chemistry/Physics/AP Physics B
Grade 12 - Physical Science/Environmental Science/Physics/Electives